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The 2019 workshop will be held in Boulder, Colorado, March 4^th- 8^th, 2019, with John Hewitt and Matt Keller as Local Hosts, and Benjamin Neale, Broad Institute and Massachusetts General Hospital, and David Evans, Diamantina Institute, University of Queensland, as co-Directors. This advanced course is intended for those who are already familiar with the statistical and genetic principles for studying human complex traits and have some familiarity with programming in R. The course will focus on statistical methods for analyzing genome-wide association studies (GWAS) and genome sequence data. Hands-on analysis will be an integral part of the course.